What is ethical research with animals? – The Chihuahua Herald

What is ethical research with animals? – The Chihuahua Herald
What is ethical research with animals? – The Chihuahua Herald

A proposed measure in Switzerland would have made that country the first to ban the medical experimentation Y scientific in animals. It did not pass in February 2022, with only 21 percent of the voters in favor. However, globally, including in the United States, there is concern about whether the research with animals is ethical.

There is no single standard definition of ethical research with animals. However, in general terms it means the humane care of the animals of research, from its acquisition and accommodation to the study experience itself.

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Federal investigative agencies follow guiding principles when evaluating the use and care of animals on the research. One is that the research should increase knowledge and, either directly or indirectly, have the potential to benefit the Health and the well-being of humans and others animals.

Another is that only the minimum number of animals necessary to obtain valid results. The researchers should use procedures that minimize pain and distress and maximize patient well-being. animals. They are also asked to consider whether they could use alternatives without animalssuch as mathematical models or computer simulations.

These principles are summarized in the “3 R’s” of research with animals: Reduction, refinement and replacement. The 3 Rs encourage scientists to develop new techniques that allow them to replace animals with suitable alternatives.

Since these guidelines were first disseminated in the early 1960s, new tools have helped to significantly decrease the animal research. In fact, since 1985, the number of animals in research has been cut in half.

A fourth “R” was formalized in the late 1990s: Rehabilitation, which refers to the care of the animals once their role in the investigation is complete.

These guidelines are designed to ensure that researchers and regulators consider the costs and benefits of using animals in research, focusing on the good that it could bring to many more animals and humans.

Enforce Ethics

Governments often set specific guidelines for ethical research with animals. Independent organizations also provide standards for research.

Beyond the basic standards for the humanitarian treatmentresearch institutions in 47 countries, including the US, can apply for voluntary accreditation from a non-profit organization called the Association for the Evaluation and Accreditation of Nursing Care. Animals of Laboratory, or AAALAC International. AAALAC accreditation recognizes the maintenance of high standards of animal care and use. It can also help recruit scientists for accredited institutes, promote scientific validity and demonstrate accountability.

Principles in practice

So what impact do these guidelines really have on research and animals?

First, they have made sure that the scientists create protocols that describe the purpose of their research and why the animals they are necessary to answer a significant question that could benefit health or medical care. While computer models and cell cultures can play an important role in some research, other studies, such as the illness of Alzheimer’s, need models animals to better capture the complexities of living organisms. The protocol should describe how animals will be housed and cared for, and who will care for and work with them, to ensure they are trained to treat animals. animals with humanity.

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During ongoing monitoring of the study, inspectors look to see if the animals they have housing designed specifically for the social and behavioral needs of their species. For example, mice are given nesting materials to create a comfortable environment in which to live and raise pups. When the animals do not have environmental stimulation, it can alter its brain function, harming not only the animal, but also the science.

Fortunately, after his time in research, some animals they may be adopted into loving homes and others may be retired to shelters and sanctuaries equipped with veterinary care, nutrition and enrichment.

research with animals benefits both humans and animals. There are numerous medical advances because they were initially studied in animals, from treatments for the cancer Y neurodegenerative diseases to new techniques for surgery, organ transplants and non-invasive imaging and diagnostics.

* Lana is a Postdoctoral Researcher in Neuroscience at the National Institutes of Health and Rachelle is a Clinical Veterinarian at Emory’s National Primate Research Center.

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The article is in Spanish

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